Lower back pain is the single leading cause of disability in 160 countries, according to the World Health Organization. It is often caused by degenerative disc disease, a progressive and irreversible condition that leads to a loss of disc height that can compress the spinal nerves and cause excruciating, intractable pain with devastating social consequences. Unfortunately, efforts to manage the condition—such as using strong painkillers including addictive opioids and performing spinal fusion surgery—are often inadequate. New and effective orthobiologic products are urgently required to address this significant unmet need.
A PDF copy of the full White Paper can be downloaded below.