Despite advances in surgical techniques and fixation, the treatment of open tibial shaft fractures continues
to be associated with high rates of delayed union and nonunion.1, 2, 3
Delayed healing of tibial fractures is reported to be more likely in the presence of infection.4, 5 which increases the risk to the patient of amputation.
Still in stealth mode – CognitOss Putty is being developed to bring together all the key advances we have made on Instructive Tissue Scaffolds from CertOss Conduit, and Programmed Drug Release of both rhBMP-2 from LDGraft and antibiotics from CognitOss Foam
*For investigational use only, not approved for sale
- Bonatus T, Olson SA, Lee S, Chapman MW. Nonreamed locking intramedullary nailing for open fractures of the tibia. Clin Orthop. 1997;339:58-64.
- Riemer BL, DiChristina DG, Cooper A, Sagiv S, Butterfield SL, Burke CJ 3rd, Lucke JF, Schlosser JD. Nonreamed nailing of tibial diaphyseal fractures in blunt polytrauma patients. J Orthop Trauma. 1995;9:66-75.
- Edwards CC, Simmons SC, Browner BD, Weigel MC. Severe open tibial fractures. Results treating 202 injuries with external fixation. Clin Orthop.
1988;230:98-115. - Caudle RJ, Stern PJ. Severe open fractures of the tibia. J Bone Joint Surg Am. 1987;69:801-7.
- Sanders R, Jersinovich I, Anglen J, DiPasquale T, Herscovici D Jr. The treatment of open tibial shaft fractures using an interlocked intramedullary nail without reaming. J Orthop Trauma. 1994;8:504-10.